Study Document
Pages:6 (2011 words)
Sources:6
Subject:Health
Topic:Hepatitis B
Document Type:Thesis
Document:#11421836
(Kanwal et al.) However, it has been found that in many cases alternative strategies to medication are often more effective. The following are a list of commonly prescribed drugs as approved by the FDA and their wholesale prices as of 2005.
Lamivudine (100 mg) - monthly cost $204- annual cost $2,482
Adefovir (10 mg) - monthly cost $546 - annual cost $6,647
Entecavir (0.5 mg) - monthly cost $715 - annual cost $8,694
Peginterferon alfa-2a (180 mcg) - monthly cost -$1,540 - annual cost $18,480
Emtricitabine (200 mg) - monthly cost $318 - annual cost $3,872
Tenofovir (300 mg) - monthly cost $478 - annual cost $5,811
( Hepatitis B Foundation, B Informed Newsletter, No. 46, Summer 2006)
References
Approved Drugs for Adults. July 17, 2009.
Kanwal et al. Treatment Alternatives for Chronic Hepatitis B Virus Infection: A Cost-
Effectiveness Analysis. Annals of Internal Medicine. Vol. 142, 10. July 17, 2009.
Hepatitis. July 17, 2009.
Hepatitis B July 17, 2009.
Hepatitis B: Brown.Edu. July 17, 2009.
Hepatitis B Foundation, B Informed Newsletter, No. 46, Summer 2006. July 17,
2009.
Hepatitis B Overview. July 17, 2009.
Hepatitis B Symptoms. July 17, 2009.
Appendix
1. Approved Hepatitis B Drugs in the United States
Interferon Alpha (Intron A) is given by injection several times a week for six months to a year, or sometimes longer. The drug can cause side effects such as flu-like symptoms, depression, and headaches. Approved 1991 and available for both children and adults.
Pegylated Interferon (Pegasys) is given by injection once a week usually for six months to a year. The drug can cause side effects such as flu-like symptoms and depression. Approved May 2005 and available only for adults.
Lamivudine (Epivir-HBV, Zeffix, or Heptodin) is a pill that is taken once a day, with few side effects, for at least one year or longer. Approved 1998 and available for both children and adults.
Adefovir Dipivoxil (Hepsera) is a pill taken once a day, with few side effects, for at least one year or longer. Approved September 2002 for adults. Pediatric clinical trials are in progress.
Entecavir (Baraclude) is a pill taken once a day, with few side effects, for at least one year or longer. Approved April 2005 for adults. Pediatric clinical trials are in progress.
Telbivudine (Tyzeka, Sebivo) is a pill taken once a day, with few side effects, for at least one year or longer. Approved October 2006 for adults.
Tenofovir (Viread) is a pill taken once a day, with few side effects, for at least one year or longer. Approved August 2008 for adults.
( Source: Approved Drugs for Adults )
See Appendix for a list of the most commonly used drugs
References
Approved Drugs for Adults. July 17, 2009.
<http://www.hepb.org/patients/hepatitis_b_treatment.htm>
Kanwal et al. Treatment Alternatives for Chronic Hepatitis B Virus Infection: A Cost-
Effectiveness Analysis. Annals of Internal Medicine. Vol. 142, 10. July 17, 2009.
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