Study Document
invasive aspergillosis: How Immunosuppression May Lead to Contraction
1. Explain why you think the patient presented the symptoms described.
The patient developed fever, cough, chest … to Contraction
1. Explain why you think the patient presented the symptoms described.
The patient developed fever, cough, chest pain, and hemoptysis because invasive aspergillosis typically begins in the lungs before spreading to other organs via the bloodstream. Once Aspergillus has infiltrated the lungs (airborne pathogenic mold), the … Identify the genes that may be associated with the development of the disease.
The following six genes are associated with the development of invasive aspergillosis: 1) NF?B1, 2) NF?B2, 3) RelA, 4) RelB, 5) REL, and 6) IRF4 (Lupianez et al., 2016). Nuclear factor kappa-light-chain enhance of activated B … immunosuppression increases the severity of infections and neoplastic diseases because the immune system is not functioning optimally.
References
Cadena, J., Thompson, G. R., & Patterson, T. F. (2016). invasive aspergillosis. Infectious Disease……
References
Cadena, J., Thompson, G. R., & Patterson, T. F. (2016). Invasive Aspergillosis. Infectious Disease Clinics of North America, 30(1), 125-142. DOI:10.1016/j.idc.2015.10.015
Lupiañez, C. B., Villaescusa, M. T., Carvalho, A., Springer, J., Lackner, M., Sánchez-Maldonado, J. M., … Sainz, J. (2016). Common Genetic Polymorphisms within NF?B-Related Genes and the Risk of Developing Invasive Aspergillosis. Frontiers in Microbiology, 7. DOI:10.3389/fmicb.2016.01243
McCance, K. L., & Huether, S. E. (2019). Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th ed.). St. Louis, MO: Elsevier Health Sciences.
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